| Jenny Fields in The World According to Garp |
| Sarah in The Big Chill |
| Iris Gaines in The Natural |
| Ruth Hillerman in The Stone Boy |
| Teddy Barnes in Jagged Edge |
| Jan in Maxie |
| Alex Forrest in Fatal Attraction |
| Marquise de Merteuil in Dangerous Liaisons |
| Ambisextra in Gandahar |
| Linda Spector in Immediate Family |
| Gertrude in Hamlet |
| Sunny von Bulow in Reversal of Fortune |
| Karin Anderson in Meeting Venus |
| Alicia Clark in The Paper |
| Diary Readings in Anne Frank Remembered |
| Cruella DeVil in 101 Dalmatians |
| Vice President Kathryn Bennett in Air Force One |
| Adrienne Pargiter in Paradise Road |
| Kala in Tarzan |
| Camille Dixon in Cookie's Fortune |
| Dr. Elaine Keener (segments "This is Dr. Keener" and "Fantasies about Rebecca") in Things You Can Tell Just by Looking at Her |
| Cruella de Vil in 102 Dalmatians |
| Esther Gold in The Safety of Objects |
| Claire Wellington in The Stepford Wives |
| Narrator in A Closer Walk |
| Diana in Heights |
| Mrs. Johnson in The Chumscrubber |
| Maggie in Nine Lives |
| Granny in Hoodwinked |
| Norma Desmond in Sunset Boulevard |
| Granny in Hoodwinked 2: Hood vs. Evil |
| Narrator in Home |
| Deb in Four Good Days |
| Nonnie in The Great Gilly Hopkins |
| Dr. Jo Scott in Swan Song |
| Narrator in Cody |
| Nicolette Cayman in What Happened to Monday |
| Albert Nobbs in Albert Nobbs |
| Gram in Low Down |
| Lady Edith de Haviland in Crooked House |
| Helen in Father Figures |
| 16080 in The Summer Book |
| Narrator in Not My Life |
| Anna Anderson in Duchess |
| Joan Castleman in The Wife |
| Morgan in The Deliverance |
| Narrator in Mind/Game: The Unquiet Journey of Chamique Holdsclaw |
| Eve in The Wilde Wedding |
| Anne Spoerry in Flight |
| Mamaw in Hillbilly Elegy |
| Narrator in Gates of the Arctic |
| 16080 in Brothers |
| Maxie in Maxie |